Ethicon’s PROLENE™ (polypropylene) suture material is generally considered biologically inert, but some potential hazards and safety considerations are associated with its use in surgical procedures.
Composition and properties
- Prolene sutures are made from an isotactic crystalline stereoisomer of polypropylene, a synthetic linear polyolefin.
- They are non-absorbable and retain their tensile strength over time.
- The suture is often dyed blue for enhanced visibility during surgery.
Potential hazards and adverse effects
While generally well-tolerated, potential issues with Prolene sutures can include foreign body reactions, infection risk, calculus formation with prolonged contact with salt solutions, and suture fracture due to instrument trauma or kinking. In some applications, such as with mesh products, complications like adhesion, erosion, and excessive contraction may occur.
Safety data sheet (SDS) information
General SDS information for polypropylene sutures indicates that the material is a stable, non-soluble solid with a melting point between 248-338 °F. Decomposition can produce carbon dioxide and carbon monoxide. Recommended handling includes avoiding contact with eyes, skin, and clothing, storing in a cool, dry area, and using personal protective equipment like dust masks and safety goggles during dust-producing operations.
Important safety reminders
Surgeons should be familiar with procedures involving non-absorbable sutures. Prolene sutures should not be resterilized or reused; opened packages and unused sutures should be discarded. Proper knot tying techniques are necessary for security. Caution should be exercised when handling needles, and used needles should be discarded in sharps containers.
Always consult the manufacturer’s specific instructions for use for complete and current information.