Compromised Collagen Formation & Hernia Development

The Role of Collagen in Hernia Genesis


  • Lars Nannestad Jorgensen
  • Finn Gottrup
  • 52Downloads


There is a discrepancy between the number of publications on hernia in general and those addressing the role of collagen as an important pathophysiological factor in the development of hernia. On Medline, the search for “hernia” produces more than 14,000 references, whereas the search for “hernia” plus “collagen” or “connective tissue” yields only 25. This difference clearly illustrates that the pathophysiological factors for hernia formation have yet to be fully defined. Many papers address different surgical techniques and their outcomes. The aim of this chapter is to give an overview of the literature on the role of collagen in hernia genesis, with a focus on biomechanical tissue features.


Inguinal Hernia Internal Ring Rectus Sheath Groin Hernia Transversalis Fascia 

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.




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